Alumni

  • Miriam Rüfenacht , B.Sc.
    Master Student
  • Raza Ali, M.D./Ph.D.
    Group Leader, CRUK Cambridge Institute
  • Pierre Bost, Ph.D.
    Marie Curie Institute
  • Marcel Burger, Ph.D.
    Wissenschaftlicher Mitarbeiter Elemental Analysis, Solvias
  • Ruben Casanova
     
  • Raúl Catena, Ph.D.
    Senior Software Engineer, Leica Geosystems
  • Stephane Chevrier, Ph.D.
    Co-founder, Navignostics AG
  • Nicolas Damond, Ph.D.
    Postdoctoral Fellow
  • Esther Danenberg, M.Sc.
    Research Administrator, CRUK Cambridge Institute
  • Michelle Daniel, M.Sc.
    Navignostics AG
  • Nadine Dobberstein, M.Sc.
    Technician, InterAx Biotech
  • Nils Eling, Ph.D.
    Senior Data Scientist, Novartis
  • Jana Fischer, Ph.D.
    Co-founder, Navignostics AG
  • Catrina Friedrich, M.Sc.
    Master's Student
  • Charlotte Giesen, Ph.D.
    Head, Quality Assurance, Roche
  • Tobias Hoch, M.Sc.
    Research Associate, Empa
  • Alexandra Huber, B.Sc.
    Master's student, ETH Zurich
  • Hartland Jackson, Ph.D.
    Group Leader, Lunenfeld-Tanenbaum Institute
  • Andrea Jacobs
    Co-founder, Navignostics AG
  • Laura Kütt, Ph.D.
    Ph.D.
  • Pieter Langerhorst, M.Sc.
    Ph.D. Student, Radboud Institute
  • Xiaokang Lun, Ph.D.
    Postdoctoral Fellow, Wyss Institute
  • Constance Lyon, M.Sc.
    Current affiliation unknown
  • Markus Masek, M.Sc.
    Ph.D. Student, University of Zurich
  • Alaz Özcan, M.Sc.
    Ph.D. Student, University of Zurich
  • Serena Di Palma, Ph.D.
    Assistant Professor, Utrecht University
  • Swetha Raghuraman, M.Sc.
    Ph.D. Student, University of Muenster
  • Luca Räss, M.Sc.
    Scientist R&D Automatization, Biognosys AG
  • Anton Rau, M.Sc.
    Software Engineer
  • Leonor Schubert Santana, M.Sc.
    Master's Student
  • Denis Schapiro, Ph.D.
    Postdoctoral Fellow, Broad Institute
  • Yannik Severin, M.Sc.
    Ph.D. Student, ETH Zurich
  • Sujana Sivapatham, M.Sc.
    Research Associate, Immunos Therapeutics
  • Merrick Strotton, Ph.D.
    Prinicpal Scientist, high-plex imaging, UCB
  • Sandra Tietscher, Ph.D.
    Business Development Manager Sensor Innovation at Sensirion
  • Marco Tognetti, Ph.D.
    Senior Scientist, Biognosys AG
  • Sophie Tritschler, M.Sc.
    Ph.D. Student, Helmholtz Z., Muenchen
  • Eleni Tselempi, M.Sc.
    Senior Research Associate, Roche Innovation Centre
  • James Wade, Ph.D.
    QSP Expert, LYO-X GmbH
  • Johanna Wagner, Ph.D.
    Postdoctoral Fellow, NCT Heidelberg
  • Jonas Windhager, Ph.D.
    Bioimage analyst, SciLife Lab
  • Shuhan Xu, M.Sc.
    Ph.D. Student, MPI
  • Vito Zanotelli, Ph.D.
    Data Analytics Consultant, D ONE
  • Nevena Zivanovic, Ph.D.
    Research Scientist, Janssen Pharmaceuticals
Miriam Rüfenacht , B.Sc.
Master Student
Raza Ali, M.D./Ph.D.
Group Leader, CRUK Cambridge Institute
Pierre Bost, Ph.D.
Marie Curie Institute
Marcel Burger, Ph.D.
Wissenschaftlicher Mitarbeiter Elemental Analysis, Solvias
Ruben Casanova
Raúl Catena, Ph.D.
Senior Software Engineer, Leica Geosystems
Nicolas Damond, Ph.D.
Postdoctoral Fellow

I am combining highly multiplexed imaging, data analysis and experimental biology to characterize type 1 diabetes (T1D) progression and beta cell heterogeneity.

I did my PhD with Prof. Pedro Herrera at the University of Geneva, studying regeneration of insulin-producing beta cells by transdifferentiation of the closely related alpha cells. During my thesis, I used confocal microscopy and lineage tracing in complex transgenic mouse models and primary human pancreatic islets. This work sparked my interest into both T1D research and image analysis of single cells, two elements that are still at the center of my current projects.

In the Bodenmiller lab, I use imaging mass cytometry to analyze pancreas sections of individuals with or at risk for type 1 diabetes. The multiplexing capacity of this technology enables deep phenotyping of beta cells and of infiltrating immune cells, and mapping of their interactions. The goal of this project is to gain a better understanding of T1D development in the pancreas.

In parallel, I'm combining primary human islet culture with imaging mass cytometry to study how beta cell subpopulations respond to external stimuli relevant to T1D. The aim is to identify beta cell subsets that are more sensitive to destructive signals or, conversely, more responsive to regenerative cues. This work is supported by a JDRF postdoctoral fellowship.

Esther Danenberg, M.Sc.
Research Administrator, CRUK Cambridge Institute
Michelle Daniel, M.Sc.
Navignostics AG
Nadine Dobberstein, M.Sc.
Technician, InterAx Biotech
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Nils Eling, Ph.D.
Senior Data Scientist, Novartis

My current research focuses on understanding the molecular changes over breast cancer organoid growth. I'm integrating imaging mass cytometry (IMC) with single-cell based statistical approaches to model spatial heterogeneity in organoids. As part of handling IMC data, I develop software for image and single-cell analysis.

In the past, I have completed my PhD in the Marioni group at the European Bioinformatics Institute and the CRUK Cambridge Institute at the University of Cambridge.

Link to website: nilseling.github.io
Link to Google Scholar: https://scholar.google.com/citations?user=kBIvrFoAAAAJ&hl=de
Link to Github: https://github.com/nilseling

Catrina Friedrich, M.Sc.
Master's Student
Charlotte Giesen, Ph.D.
Head, Quality Assurance, Roche
Tobias Hoch, M.Sc.
Research Associate, Empa

As a research assistant and former Master's student in the lab, I am currently analyzing IMC data with a focus on the immune system and its relation to the protein family of chemokines. I am investigating whether and to what extent the spatial context of chemokine expression can contribute to understanding differences in the immune landscape of patients.

Alexandra Huber, B.Sc.
Master's student, ETH Zurich
Hartland Jackson, Ph.D.
Group Leader, Lunenfeld-Tanenbaum Institute
Laura Kütt, Ph.D.
Ph.D.
Pieter Langerhorst, M.Sc.
Ph.D. Student, Radboud Institute
Xiaokang Lun, Ph.D.
Postdoctoral Fellow, Wyss Institute
Constance Lyon, M.Sc.
Current affiliation unknown
Markus Masek, M.Sc.
Ph.D. Student, University of Zurich
Alaz Özcan, M.Sc.
Ph.D. Student, University of Zurich
Serena Di Palma, Ph.D.
Assistant Professor, Utrecht University
Swetha Raghuraman, M.Sc.
Ph.D. Student, University of Muenster
Luca Räss, M.Sc.
Scientist R&D Automatization, Biognosys AG
Anton Rau, M.Sc.
Software Engineer
Leonor Schubert Santana, M.Sc.
Master's Student
Denis Schapiro, Ph.D.
Postdoctoral Fellow, Broad Institute
Yannik Severin, M.Sc.
Ph.D. Student, ETH Zurich
Sujana Sivapatham, M.Sc.
Research Associate, Immunos Therapeutics
Merrick Strotton, Ph.D.
Prinicpal Scientist, high-plex imaging, UCB
Sandra Tietscher, Ph.D.
Business Development Manager Sensor Innovation at Sensirion
Marco Tognetti, Ph.D.
Senior Scientist, Biognosys AG
Sophie Tritschler, M.Sc.
Ph.D. Student, Helmholtz Z., Muenchen
Eleni Tselempi, M.Sc.
Senior Research Associate, Roche Innovation Centre
James Wade, Ph.D.
QSP Expert, LYO-X GmbH
Johanna Wagner, Ph.D.
Postdoctoral Fellow, NCT Heidelberg

Selected Publications

Jonas Windhager, Ph.D.
Bioimage analyst, SciLife Lab
Shuhan Xu, M.Sc.
Ph.D. Student, MPI
Vito Zanotelli, Ph.D.
Data Analytics Consultant, D ONE

I like to develop high throughput methods together with tailored data analysis approaches to better understand how cells perceive their environment and interact.

Nevena Zivanovic, Ph.D.
Research Scientist, Janssen Pharmaceuticals